The Top 6 Anti-Aging Supplements

In 2006 when Harriet died, she was just about 175 years old. Of course, Harriet was not a human. She was a Galapagos tortoise, and she lived at a zoo in Australia. When compared with humans, Harriet had a very long life. The Galapagos tortoise is not the only living thing with such a remarkable capability to live long. Ocean quahogs can live more than 400 years, while trees such as bristlecone pine can even live for thousands of years.

Yet, humans, who are considered to be at the apex of terrestrial life, do well to live only for 70 or 80 years. Why such a significant difference, you may ask? Are seven decades, or so, the best humans can hope for? Or is there anything that can be done to extend human longevity? What is the secret of living longer? Finding the answer to these questions might help you to live much longer. In this article, we will provide satisfying solutions that are based on scientific evidence to these questions. Mainly, we will be detailing the six top supplements that hold the key to longevity.

What are the greatest enemies of longevity?

The quest for the secret of long life is almost as old as life itself. Both ancient and modern scientists have made incredible advances in finding answers to why we grow old and die. Thus, it is not surprising to see many ideas explaining the evil enemy behind aging. These include living a sedentary lifestyle, which can lead to the loss of muscle mass, dehydration, and poor nutrition. Also, stress can weaken the immune system, insomnia, alcohol abuse, lack of social ties, and the alteration in the genetic program for development, which is also referred to as the DNA damage theory of aging. Among all the methods that have been proposed, the DNA damage theory, which explains that genome instability plays a critical role in the process of aging, has gotten serious attention recently. Many scientists believe that this critical event that constantly takes place within the cell is the key enemy to longevity. Unfortunately, the human genome (total genetic makeup of an organism) is continuously under genotoxic attack (e.g. oxidative damage), which eventually leads to DNA damage, thereby causing the genetic programs for development to go awry. Scientists have been working tirelessly to search for novel substance/therapeutics that can prevent or slow down this inevitable process. Scientists have been able to identify different substances that have anti-aging properties, many of which can be taken as supplements. In this article, we will highlight the top six of such supplements with anti-aging properties

What are the six top supplements that hold the key to longevity?

Several supplements have been shown to have anti-aging effects. However, the best of such supplements on the market today are shown below.

1.     Metformin: Metformin is a unique biguanide compound primarily derived from a guanidine derivative found in the Galega officinalis plant. Metformin can slow down the aging process and appearance of age-related diseases such as diabetes mellitus, fatty liver, macrovascular disease, colon, and pancreatic cancer, dementia, and other cognitive impairment. Metformin elicits its favorable anti-aging properties by targeting and modulating conserved pathways associated with aging at the cellular and organismal levels. One of the critical mechanisms is their ability to reduce the production of reactive oxygen species (ROS), thereby reducing oxidative DNA damage.

2.     Low Dose Naltrexone (LDN):  Do you feel hurt all over? Is falling asleep taking forever? Are you extraordinarily fatigued or tired? On awakening in the morning, are you stiff and exhausted? Is your memory impeded at times? These no doubt are some of the few symptoms of those who have age-related diseases such as inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, lupus, Crohn’s disease, and others autoimmune disorders faces. These devastating symptoms have stolen the peace, joy, and livelihood of millions of people, making life so miserable. Nevertheless, despite these horrible signs, those suffering from these conditions can still find relief. The wonder lies in the power of “Low Dose Naltrexone (LDN).” LDN works by increasing the levels of endorphins. Endorphins (internal opioids) are peptides produced in the brain and adrenal glands, which help in relieving pain and enhancing the overall sense of well-being. These natural peptides are also potent modulators of the immune system. Research evidence indicates that when LDN is taken at bedtime, it attaches to opioid receptors and briefly blocks endorphins from attaching, causing the body to increase endorphins production. This is how LDN enhances the body’s ability to fight disease.

3.     NAD+ PATCHES: Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor found in all cells in your body. It is involved in many fundamental biological processes such as energy metabolism, DNA repair, and gene expression. NAD+ depletion is one of the hallmarks of aging. This decline has been thought to be associated with a wide range of age-related diseases, such as metabolic disorders, cancer, neurodegenerative diseases, and physical decline. However, emerging evidence stemming from recent studies have shown that elevation of NAD+ levels may slow or even reverse aging and age-related diseases. Various laboratory animal studies have shown that NAD+ supplement can help boost NAD+ levels and prevents age-related physical decline. is a great resource for more information on NAD+ Patches as well as other anti-aging supplements.

4.     Coenzyme Q10 (CoQ10): CoQ10 is an essential endogenous antioxidant that your body produces. It plays a vital role in energy production and protects against cellular damage. However, studies have shown that this essential molecule diminishes with advancing age. The decrease of CoQ10 levels during aging could be one of the main reasons to develop chronic diseases in the aged. Research using both humans and rodents has suggested that supplementing CoQ10 has been shown to improve older individuals’ overall quality of life, especially under certain conditions associated with increased oxidative stress. CoQ10 supplements help reduce oxidative stress, thereby preventing DNA damage, which can accelerate the aging process and onset of age-related disease. Also, CoQ10 has shown therapeutic benefits in aging-related disorders, particularly in cardiovascular and metabolic diseases.

5.     Collagen protein: Collagen is the most abundant protein in the body. It is found in bone, cartilage, tendons, ligaments, and skin. It reduces wrinkles and sagging by ensuring the skin cells adhere to one another, thereby improving the elasticity and strength of the skin. Also, collagen naturally does pack a dose of glycine, an amino acid that supports more restful sleep, thereby helping you to sleep better. Unfortunately, this protein production declines as you age. Thus, to continue to benefit from collagen, it is essential to take collagen supplements to boost these essential molecules.

6.     Fisetin: is a plant chemical (flavonoids) with profound therapeutic properties. Research has suggested that Fisetin can help reduce senescence. Cell senescence is a tumor suppressor mechanism activated in stressed cells to prevent the replication of damaged DNA. This mechanism has been demonstrated to play a critical role in driving aging and age-related diseases using genetic and pharmacologic approaches. Taking Fisetin supplements can help halt senescence, thereby reducing age-related pathology and eventually extending the human lifespan. Furthermore, it is a molecule with antioxidant properties Like other antioxidants. It helps protect your cells from free radicals, thereby preventing DNA damage. 

Final remark

With all the facts highlighted in this article, there is no doubt that these six supplements (especially; MetforminLow Dose Naltrexone, and NAD+ PATCHES) are the hope we have all been waiting for. They are effective, safe, and affordable. For more information about longevity science and longevity treatments visit Why not get started with these supplements today. It will help you to live much longer than seems possible at present.



Health & Fitness

Photo of author


I work as a full time hair stylist but love writing about life. I hope to become a full time writer one day and spend all my time sharing my experience with you!

Leave a Comment